Once you have Configured all your desired options through Ninite Solutions interface you are able to start performing updates by running the MP - Ninite - Application Maintenance. There are a number of ways that this script can be scheduled to perform maintenance on a regular basis.
Recommended Configuration
These steps outline enabling Ninite Solution on the Service Plan: Managed 24x7 for Windows Workstations only.
in the LabTech Control Center navigate to: Groups > Service Plans > Windows Workstations > Managed 24x7
Right click on the group Managed 24x7 and select Edit Group
Navigate to the Scripts tab and schedule the Ninite Maintenance Script
Ensure that you update the schedule to meet your requirements